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The Center for Human Genetic Research, or CHGR, is one of four recently created thematic
centers at MGH. The CHGR will occupy 60,000 square feet of laboratory, office and clinical
phenotyping space in the new Charles River Plaza research building, which is scheduled to
open in May, 2005. The CHGR is a multidisciplinary cross-departmental center that has as
its central mission the facilitation of the genetic research cycle:
Definition of phenotypic variation in patient populations.
Isolation of genes underlying the phenotypic variation.
Characterization in humans and model systems of the mechanisms that lead from genotype to phenotype
use of these findings to provide better diagnostic capacity, disease management and effective
treatments to the patient population.
